Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment The Use of Biomarkers in Carcinogenic Risk Assessment
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چکیده
1. A biomarker is any substance, structure or process that can be measured in an organism, related to a specific exposure or effect or which can influence the incidence of the effect. Biomarkers can provide valuable information to aid chemical risk assessment processes and are used as investigative tools in both animal and human studies which aim to evaluate carcinogenic hazards and risk. The over-arching summary Guidance Statement (G01) provides the Committee’s views on the general principles relating to carcinogenic hazard and risk assessment and a background to the individual components of the risk assessment process and how these are integrated. This statement aims to provide detail of how biomarkers are utilised within the individual components of the risk assessment process.
منابع مشابه
Scientific Committee on Health and Environmental Risks SCHER Scientific Committee on Consumer Products SCCP Scientific Committee on Emerging and Newly Identified Health Risks SCENIHR Risk assessment methodologies and approaches for genotoxic and carcinogenic substances
Genotoxic and carcinogenic substances 2 Three independent non-food Scientific Committees provide the Commission with the scientific advice it needs when preparing policy and proposals relating to consumer safety, public health and the environment. The Committees also draw the Commission's attention to the new or emerging problems which may pose an actual or potential threat. SCHER Questions rel...
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